<jats:p>Ashwagandha root extract has grade A evidence, and is recommended for monotherapy or adjunctive use in GAD. Take 300–600 mg/day standardized to 5% withanolides. Be cautious when considering ashwagandha in patients with pre-existing thyroid disorders or taking thyroid medications. A baseline TSH is recommended before starting it in those cases. Chamomile extract 500 mg three times daily produced 58% response in GAD, comparable to conventional anxiolytics.</jats:p>