Abstract
<jats:p>Peste des petits ruminants (PPR) is a highly contagious viral disease that severely impacts sheep and goats, leading to significant morbidity and mortality. This study focuses on the macroscopic lesions (oral, lung, gastrointestinal) identified in sheep from collection centers in Tulcea County, an area at high risk for PPR transmission. The aforementioned lesions were documented in animals suspected of PPR infection and linked to the disease’s characteristic clinical signs. The insights gained from these observations are critical for early differential and then presumptive diagnosis, these steps being crucial for guiding effective control strategies to limit the spread of the virus. This case report highlights the importance of necropsy-based diagnosis in early detection and outbreak control of PPR in endemic risk areas.</jats:p>