Abstract
<title>Abstract</title> <p> <bold>Objective:</bold> To explore factors influencing self-management and patient preferences for program design among Jordanian adults with coexisting knee osteoarthritis (KOA) and overweight or obesity. <bold>Design:</bold> A qualitative study was conducted using in-depth, semi-structured interviews guided by the SEM. Participants were purposively recruited from outpatient rehabilitation units in two hospital-based clinical settings in Jordan. Eligible participants were adults diagnosed with mild to moderate KOA and classified as overweight or obese. Interviews were audio-recorded, transcribed verbatim, and analyzed using thematic analysis to identify barriers, facilitators, and preferences related to self-management. <bold>Results:</bold> The analysis generated three overarching domains—barriers, facilitators, and patient preferences for self-management—comprising eight themes and nineteen subthemes. Barriers included four themes: health system–related barriers, social and cultural influences, behavioral and psychological factors, and health-related limitations. Facilitators comprised two themes: supportive resources and strategies and social and lifestyle enablers. Patient preferences were reflected in two themes: preferred delivery methods and desired program content. <bold>Conclusions:</bold> This study identifies novel cultural, environmental, and gendered barriers to self-management of coexisting KOA and obesity in Jordan, underscoring the interplay of individual, interpersonal, and community-level factors. Culturally sensitive interventions, tailored to patient needs and preferences and supported by family, healthcare providers, and digital tools, are likely to enhance engagement, adherence, and outcomes. These insights will directly inform the development of patient-centered, contextually relevant self-management programs for individuals with KOA and overweight or obesity in Jordan and comparable settings. </p>