Abstract
<title>Abstract</title> <p> <bold>Background</bold> Effective pharmacovigilance practices optimize outcomes and reduce health risks with medication use. However professionals report only 5–10% of adverse drug reactions (ADRs), mainly because of limited knowledge and lack of awareness of the importance of ADRs reporting. Educational interventions have been shown to improve pharmacovigilance practices. Therefore the aim of this study is to evaluate the impact of a pharmacovigilance training course on the knowledge of Mexican healthcare providers. <bold>Methods</bold> A quasiexperimental study was conducted, including participants enrolled in a pharmacovigilance course. The primary outcome was the mean difference between precourse and postcourse assessment scores. <bold>Results</bold> Of 553 participants, 404 were eligible for the final sample. Mean examination scores increased from 5.42 (SD 2.14) at baseline to 7.72 (SD 2.05) after intervention, representing a mean improvement of 2.30 points (SD 2.36; p < 0.001). <bold>Conclusions</bold> Health-related educational interventions can be effective and improve pharmacovigilance knowledge among healthcare professionals. The project was approved by the Institutional Review Board from the National Institute of Geriatrics in Mexico with the approval number: DI-PI-007/2025 </p>