Abstract
<title>Abstract</title> <p>Background Saudi Arabia’s National Hepatitis C Virus (HCV) Elimination Programme aims to meet WHO’s 2030 targets through mass screening, decentralised treatment, and public awareness. Healthcare workers (HCWs) are central to this effort, yet their perspectives on system-level challenges remain understudied. Aims This study explores HCWs’ experiences with the national HCV programme to evaluate operational performance, identify systemic barriers, and highlight opportunities to improve care pathways. Methods A qualitative design using semi-structured interviews was conducted with 21 HCWs (including physicians, nurses, lab staff, and administrators) across 15 treatment centres in five Saudi regions. Data were analysed inductively using thematic analysis. Results While HCWs expressed strong commitment, they reported that programme delivery relies heavily on individual initiative rather than structured institutional support. Screening intensity has declined due to rapid-test shortages and limited public awareness. Centralised PCR testing caused diagnostic delays, contributing to patient disengagement, while treatment capacity remains underutilised due to weak linkage to care. Key systemic barriers include supply chain instability, inconsistent administrative communication, limited formal training, and patient stigma. HCWs recommended decentralising diagnostics, stabilizing supply chains, and enhancing community engagement. Conclusion Saudi Arabia’s HCV elimination goals are supported by a motivated workforce but constrained by operational inefficiencies. Strengthening logistics, inter-level coordination, and community outreach is essential to achieve sustainable national elimination.</p>