Figure 3 from Febuxostat Enhances the Antitumor Efficacy of 2-Fluoroadenine and 5′-Methylthioadenosine in <i>MTAP</i>-Deleted Cancer

<jats:p>&lt;p&gt;XO inhibits 2FA toxicity. &lt;b&gt;A,&lt;/b&gt; Growth inhibition of HT1080 &lt;i&gt;MTAP&lt;/i&gt;+ cells treated with various concentrations of 2FA for 48 hours in the presence or absence of either MTA or XO. &lt;b&gt;B,&lt;/b&gt; Effect of the XO inhibitor FX on XO protection. &lt;i&gt;N&lt;/i&gt; = 4 per point; error bars show SEM. Different letters next to points indicate significant differences.&lt;/p&gt;</jats:p>