Data from Cancer-Related Pain and Sexual Orientation and Gender Identity: An Intersectional Approach

<jats:p>&lt;div&gt;Abstract Background:&lt;p&gt;We examined cancer-related pain in sexual and gender minorities (SGM) compared with heterosexual cisgender populations and evaluated sociodemographic factors within SGM and heterosexual cisgender cancer survivors.&lt;/p&gt; Methods:&lt;p&gt;We combined 2014 to 2023 data of the Behavioral Risk Factor Surveillance System from 23 states and Guam that administered the sexual orientation and gender identity module and the pain-specific cancer survivorship module. Our analytic sample consisted of 56,217 cancer survivors, 1,655 of whom identified as SGM.&lt;/p&gt; Results:&lt;p&gt;Sexual minority cancer survivors reported twice or more the prevalence of cancer pain than heterosexual cisgender survivors, with gender minority cancer survivors reporting cancer pain most frequently (28%), followed by sexual minority women (17%), and sexual minority men (14%). Sociodemographic subgroups, consisting of younger, unmarried, not employed, and those with low income, are at increased risk of experiencing cancer pain.&lt;/p&gt; Conclusions:&lt;p&gt;Our findings point to heterogeneity among sexual minority cancer survivors’ prevalence of pain and additional efforts to characterize gender minorities’ disparities in cancer pain.&lt;/p&gt; Impact:&lt;p&gt;There is an urgent need for evidence-based real-life clinical data characterization of SGM cancer pain disparities and efforts to reduce their cancer-related pain.&lt;/p&gt;&lt;p&gt;&lt;i&gt;&lt;a target="_blank" href="https://aacrjournals.org/cebp/article/doi/10.1158/1055-9965.EPI-26-0496"&gt;See related In the Spotlight, p. 1236&lt;/a&gt;&lt;/i&gt;&lt;/p&gt;&lt;/div&gt;</jats:p>