Figure S14 from SETD2 Deficiency Drives Mitochondrial DNA Leakage and Creates a Druggable Dependency on BCL-xL in Clear Cell Renal Cell Carcinoma

<jats:p>&lt;p&gt;Figure S14. TBK1 was deleted using CRISPR/Cas9 in SETD2 WT and SETD2-deficient 786-O cells. Cells were treated with DMSO or 100nM A-1331852 for 72 hours and harvested to assess inflammatory signaling and NOXA expression by immunoblot. Actin was used as a loading control.&lt;/p&gt;</jats:p>