Figure S19 from SETD2 Deficiency Drives Mitochondrial DNA Leakage and Creates a Druggable Dependency on BCL-xL in Clear Cell Renal Cell Carcinoma

<jats:p>&lt;p&gt;Figure S19. SETD2 WT and SETD2-deficient A498 cells were treated with ethidium bromide to deplete mitochondrial DNA (mtDNA). Cells were subsequently treated with DMSO or 100nM A-1331852 for 72 hours, and total DNA was isolated. mtDNA levels were quantified by qPCR. GAPDH was used as an endogenous reference.&lt;/p&gt;</jats:p>