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Abstract
<jats:title>Abstract</jats:title> <jats:p> This chapter summarizes key considerations for antimicrobial susceptibility testing of fastidious and infrequently isolated bacteria. Up‐to‐date data on the global incidence of resistance, as documented by international, national, and local surveillance studies for these organisms, are presented. Important resistance mechanisms are discussed for many organisms, including <jats:italic>Streptococcus</jats:italic> spp., <jats:italic>Haemophilus influenzae, Neisseria gonorrhoeae,</jats:italic> and <jats:italic>Neisseria meningitidis</jats:italic> . This chapter also describes standard methods for testing the infrequently isolated or fastidious bacteria included in the CLSI M100 standard, M2, M7, and M45 guidelines, as well as in the EUCAST standards. </jats:p>